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DiscoverX ALK2, active 14-937M

品牌：Eurofins DiscoverX

貨號(hào)：14-937M

規(guī)格：14-937M

貨期：DiscoverX

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品牌：DiscoverX 品名：ALK2, active 貨號(hào)：14-937M 規(guī)格：250 μg

商品詳情參考文獻(xiàn) 相關(guān)資料

品牌：DiscoverX
品名：ALK2, active
貨號(hào)：14-937M
規(guī)格：250 μg

簡(jiǎn)要說(shuō)明：

ALK2, active

N-terminal 6His-tagged recombinant, human ALK2 amino acids 147-end.Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

產(chǎn)品介紹：

Target

ALK2

Expression System

Expressed by baculovirus in Sf21 insect cells

Application

Kinase Assay

Molecular Weight

45 kDa

Accession Number

NM_001105

Species

Human

Tag

6His

Purification Method

Immobilised metal affinity chromatography

Content

Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.

Storage

6 months at -70°C

Bulk Sizes

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