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DiscoverX TYK2, active 14-924M

品牌：Eurofins DiscoverX

貨號：14-924M

規(guī)格：14-924M

貨期：DiscoverX

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品牌：DiscoverX 品名：TYK2, active 貨號：14-924M 規(guī)格：250 μg

商品詳情參考文獻(xiàn) 相關(guān)資料

品牌：DiscoverX
品名：TYK2, active
貨號：14-924M
規(guī)格：250 μg

簡要說明：

TYK2, active

N-terminal 6His-tagged recombinant, human TYK2 amino acids 875-end. TYK2 is member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

產(chǎn)品介紹：

Target

TYK2

Expression System

Expressed by baculovirus in Sf21 insect cells

Application

Kinase Assay

Molecular Weight

40 kDa

Accession Number

NM_003331

Species

Human

Tag

6His

Purification Method

Immobilised metal affinity chromatography; Gel filtration

Content

Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.

Storage

6 months at -70°C

Bulk Sizes

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