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DiscoverX TrkC, active 14-922-K

品牌：Eurofins DiscoverX

貨號(hào)：14-922-K

規(guī)格：14-922-K

貨期：DiscoverX

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品牌：DiscoverX 品名：TrkC, active 貨號(hào)：14-922-K 規(guī)格：Bulk

商品詳情參考文獻(xiàn) 相關(guān)資料

品牌：DiscoverX
品名：TrkC, active
貨號(hào)：14-922-K
規(guī)格：Bulk

簡(jiǎn)要說(shuō)明：

TrkC, active

N-terminal GST-tagged and C-terminal 6His-tagged recombinant, human TrkC amino acids 510-end. TrkC is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.

產(chǎn)品介紹：

Target

TrkC

Expression System

Expressed by baculovirus in Sf21 insect cells

Application

Kinase Assay

Molecular Weight

64 kDa

Accession Number

NM_002530

Species

Human

Tag

GST, 6His

Purification Method

Glutathione agarose affinity chromatography; Gel filtration

Content

Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.

Storage

6 months at -70°C

Bulk Sizes

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