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DiscoverX CLK1, active 14-920-K

品牌：Eurofins DiscoverX

貨號(hào)：14-920-K

規(guī)格：14-920-K

貨期：DiscoverX

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品牌：DiscoverX 品名：CLK1, active 貨號(hào)：14-920-K 規(guī)格：Bulk

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品牌：DiscoverX
品名：CLK1, active
貨號(hào)：14-920-K
規(guī)格：Bulk

簡要說明：

CLK1, active

N-terminal 6His-tagged recombinant, human CLK1 amino acids 130-end.CLK1 is a dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.

產(chǎn)品介紹：

Target

CLK1

Expression System

Expressed by baculovirus in Sf21 insect cells

Application

Kinase Assay

Molecular Weight

45 kDa

Accession Number

NM_004071

Species

Human

Tag

6His

Purification Method

Immobilised metal affinity chromatography

Content

Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.

Storage

6 months at -70°C

Bulk Sizes

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