Catalogue number
IHA-024
Introduction
H3N2 is a subtype of the influenza A virus. Its name derives from the forms of the two kinds of proteinson the surface of its coat, hemagglutinin(H) and neuraminidase(N). H3N2 exchanges genes for internal proteins with other influenza subtypes. H3N2 has tended to dominate in prevalence over H1N1, H1N2, and influenza B. H3N2 strain descended from H2N2by antigenic shift, in which genes from multiple subtypes re-assorted to form a new virus. Both the H2N2and H3N2 strains contained genesfrom avian influenzaviruses.
Description
Allantoic fluid of 10 days old embryonated eggs, inoculated with influenza A virus, strain A/Brisbane/10/07. The Influenza Virus was purified by Ultracentrifugation with 10-40 % sucrose gradient.
Inactivation
Thimerosal and beta propiolactone treatment
This product has been treated in a manner consistent with methods of inactivation. Generally accepted good laboratory practices appropriate to microbiological/viral safe handling practices and techniques are required at work.
Physical Appearance
Sterile Filtered whitish (milky) solution.
Formulation
The H3N2 A/Brisbane/10/07 solution contains STE, 0.1% sodium azide (NaN3) and 0.005% thimerosal.
Stability
A/Brisbane/10/07although stable 4°C for 4 weeks, should be stored below -18°C.
Please prevent freeze-thaw cycles.
Immunological Activity
Tested with anti-influenza A monoclonal antibodies in ELISA.
Serological studies of influenza A virus, immunogen for antibody production.
Purity
Greater than 90.0% as determined byAnalysis by SDS-PAGE.
References
Title: Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection
publication: The Rockefeller University Press, doi: 10.1084/jem.20101352
? 2011 Wrammert et al.
Link:http://jem.rupress.org/content/early/2011/01/06/jem.20101352.full
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
