Catalogue number
ANT-517
Synonyms
35DAG, CMD1L, DAGD, SG-delta, SGCDP, SGD,
Delta-sarcoglycan, 35 kDa dystrophin-associated glycoprotein.
Type
Mouse Anti Human Monoclonal.
Introduction
Sarcoglycan Delta (SGCD) is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC) and is expressed mainly in skeletal and cardiac muscle. DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. SGCD protein’s mutations have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. SGCD gene expression is regulated by MITF In melanocytic cells.
Clone
PAT19G8AT.
Physical Appearance
Sterile filtered colorless solution.
Immunogen
Anti-human SGCD mAb, clone PAT19G8AT,
is derived from hybridization of mouse F0 myeloma cells with spleen cells from
BALB/c mice immunized with a recombinant human SGCD protein 57-289 amino
acids purified from E. coli.
Ig Subclass
Mouse
IgG1 heavy chain and k light chain.
Purification Method
SGCD
antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Formulation
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Storage Procedures
For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C.?
Prevent freeze thaw cycles.
Stability / Shelf Life
12 months at -20°C. 1 month at 4°C.
Applications
The antibody has been tested by ELISA, Western blot
analysis to assure specificity and reactivity. Since application varies,
however, each investigation should be titrated by the reagent to obtain optimal
results. Recommended starting dilution is 1:1000.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
