Catalogue number
ENZ-834
Synonyms
N-6 Adenine-Specific DNA Methyltransferase 1 (Putative), N(6)-Adenine-Specific
DNA Methyltransferase 1, HemK Methyltransferase Family Member 2, M.HsaHemK2P, C21orf127,
HEMK2, Chromosome 21 Open Reading Frame 127, N6-DNA-Methyltransferase, EC
2.1.1.- , PRED28, N6AMT, MTQ2, HemK methyltransferase family member 2.
Introduction
N-6 Adenine-Specific DNA Methyltransferase 1, also known as N6AMT1 is
part of the methyltransferase family. N6AMT1 is implicated in the methylation
of release factor I? during translation
termination. In addition, N6AMT1 is involved in converting the arsenic
metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid.?
Description
N6AMT1 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 237 amino acids (1-214 a.a) and
having a molecular mass of 25.3kDa.
N6AMT1 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
N6AMT1 protein solution (0.25 mg/ml) containing Phosphate
buffered saline (pH7.4), 20% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMAGENFA TPFHGHVGRG AFSDVYEPAE DTFLLLNALE AAAAELAGVE
ICLEVGSGSG VVSAFLASMI GPQALYMCTD INPEAAACTL ETARCNKVHI QPVITDLVKG LLPRLTEKVD
LLVFNPPYVV TPPQEVGSHG IEAAWAGGRN GREVMDRFFP
LVPDLLSPRG LFYLVTIKEN NPEEILKIMK TKGLQGTTAL SRQAGQETLS
VLKFTKS.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
