Catalogue number
ENZ-928
Synonyms
Glutathione
S-transferase P 2 (EC:2.5.1.18), Gst P2, GST YF-YF, GST class-pi, GST-piA, Gstp2,
Gstpia.
Introduction
Gltathione S-transferase PI 2, also known as GSTP2 is multifunctional
enzyme which is involved in the protection of
cellular components against anti-cancer drugs or peroxidative stress. Furthermore,
down regulation of GSTP2 induces an increase
of oxidative damage in the pyramidal cells of the CA1&CA3 regions as well
as in the granular layer of the dentate gyrus, which
at the end leads to structural and functional damage.
Description
GSTP2 Mouse Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 233 amino acids (1-210 a.a) and
having a molecular mass of 25.9kDa. GSTP2 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile
filtered colorless solution.
Formulation
GSTP2 protein solution (1mg/ml) containing Phosphate
Buffered Saline (pH 7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater
than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMPPYTIV YFPSPGRCEA MRMLLADQGQ SWKEEVVTID TWMQGLLKPT
CLYGQLPKFE DGDLTLYQSN AILRHLGRSL GLYGKNQREA AQVDMVNDGV EDLRGKYGTM IYRNYENGKN
DYVKALPGHL KPFETLLSQN QGGKAFIVGD QISFADYNLL DLLLIHQVLA PGCLDNFPLL
SAYVARLSAR PKIKAFLSSP EHVNRPINGN GKQ.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
