Catalogue number
ANT-020
Synonyms
FKBP22, FKBP-14, FK506 Binding Protein 14, FKBP14, EC=5.2.1.8, PPlase FKBP14, Peptidyl-prolyl cis-trans isomerase FKBP14, FLJ20731.
Type
Mouse Anti Human Monoclonal.
Introduction
FKBP14 enzyme accelerates the folding of proteins during protein synthesis. FKBP14 contains 2 EF-hand domains and one PPIase FKBP-type domain. Truncation of the amino-terminus of FKBP14 significantly decreases peptidyl prolyl cis-trans isomerase activity, therefore implicating that the PPIase FKBP-type domain must be located at the N-terminus.
Clone
PAT18E2AT.
Immunogen
Anti-human FKBP14 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human FKBP14 amino acids 20-211 purified from E. coli.
Ig Subclass
Mouse IgG1 heavy chain and?k light chain.
Purification Method
FKBP14 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Formulation
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Storage Procedures
For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life
12 months at -20°C. 1 month at 4°C.
Applications
FKBP14 antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
