Catalogue number
PRO-1893
Synonyms
DKFZp666D049, FLJ23153, STAMP2, TIARP, TNFAIP9, Six-transmembrane
epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, Tumor
necrosis factor, alpha-induced protein 9.
Introduction
STEAP Family Member 4
(STEAP4) is a member of the STEAP (six transmembrane epithelial antigen of
prostate) family, resides in the golgi apparatus. STEAP4 act as a
metalloreductase which has the ability to reduce both Fe(3+) to Fe(2+) and
Cu(2+) to Cu(1+),using NAD(+) as acceptor. According to studies in mice and
human it is possible that STEAP4 may involve in adipocyte development and
metabolism, and also contribute to the normal biology of the prostate cell.
Description
STEAP4 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 188 amino acids (1-152 a.a) and
having a molecular mass of 20.6kDa.STEAP4 is fused to a 36 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
STEAP4 protein solution (1mg/ml) contains 20mM Tris-HCl
buffer (pH 8.0), 0.4M UREA and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMEKT CIDALPLTMN SSEKQETVCI FGTGDFGRSL GLKMLQCGYS
VVFGSRNPQK TTLLPSGAEV LSYSEAAKKS GIIIIAIHRE HYDFLTELTE VLNGKILVDI SNNLKINQYP
ESNAEYLAHL VPGAHVVKAF NTISAWALQS GALDASRQ.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
