Catalogue number
ENZ-079
Synonyms
Protein syndesmos, NUDT16-like protein 1, NUDT16L1, SDOS, MGC11275.
Introduction
Syndesmos (NUDT16L1) is a cytoplasmic protein which interacts specifically with the cytoplasmic domain of syndecan-4, and co-localizes with syndecan-4 in focal contacts. NUDT16L1 interacts with the focal adhesion adaptor protein paxillin. The binding of NUDT16L1 to paxillin is direct, and these interactions are triggered by the activation of protein kinase C.
Description
NUDT16L1 Human Recombinant fused with a?20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing?231 amino acids (1-211 a.a.) and having a molecular mass of 25.5kDa. The NUDT16L1 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The NUDT16L1 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.?
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MSTAAVPELK QISRVEAMRL GPGWSHSCHA MLYAANPGQL FGRIPMRFSV LMQMRFDGLL GFPGGFVDRR FWSLEDGLNR VLGLGLGCLR LTEADYLSSH LTEGPHRVVA HLYARQLTLE QLHAVEISAV HSRDHGLEVL GLVRVPLYTQ KDRVGGFPNF LSNAFVSTAK CQLLFALKVL NMMPEEKLVE ALAAATEKQK KALEKLLPAS S.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
