Catalogue number
ANT-156
Type
Mouse antibody Monoclonal.
Introduction
HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Immunogen
Recombinant HCV NS-3 (genotype 1a).
Ig Subclass
Mouse IgG1.
Description
MAb to HCV NS-3, Monoclonal Antibody to Hepatitis C Virus (HCV), NS-3.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a solution containing no additives.
Stability
24 months when stored frozen prior to reconstitution.
Avoid multiple freeze/thaw cycles.
Specificity
Recognizes Hepatitis C virus. Specific to NS-3.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
