Catalogue number
ANT-616
Synonyms
ADK2, AK-2, Adenylate kinase isoenzyme 2 mitochondrial,
ATP-AMP transphosphorylase 2, adenylate kinase 2.
Type
Mouse Anti Human Monoclonal.
Introduction
Adenylate kinases plays a role in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. There are 3 types of adenylate kinase isozymes, AK1, AK2, and AK3 in vertebrates. Expression of these isozymes are tissue-specific and developmentally regulated. AK2 is localized in the mitochondrial intermembrane space and is involved in apoptosis. AK2 is mutated in individuals with reticular dysgenesis.
Clone
PAT7E7AT.
Physical Appearance
Sterile filtered colorless solution.
Immunogen
Anti-human AK2 mAb, is
derived from hybridization of mouse F0 myeloma cells with spleen cells from
BALB/c mice immunized with a recombinant human AK2 protein 1-239 amino
acids purified from E. coli.
Ig Subclass
Mouse
IgG1 heavy chain and k light chain.
Purification Method
AK2
antibody was purified from mouse ascitic fluids by protein-A affinity
chromatography.
Formulation
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Storage Procedures
For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C.?
Prevent freeze thaw cycles.
Stability / Shelf Life
12 months at -20°C. 1 month at 4°C.
Applications
The antibody has been tested by ELISA, Western
blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity.
Since application varies, however, each investigation should be titrated by the
reagent to obtain optimal results.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
