Catalogue number
PRO-1727
Synonyms
OSTB, OSTBETA, Organic solute transporter subunit beta, OST-beta,
Solute carrier family 51 subunit beta.
Introduction
Solute Carrier Family 51 Beta (SLC51B), is a protein coding gene. SLC51B
is an organic solute transporter subunit. SLC51 is composed of two different proteins
that must heterodimerize to generate transport activity, however the role of
the individual subunits in
mediating transport activity is unknown. The results show that SLC51B is
required for both proper trafficking of SLC51A and formation of the functional transport
unit, and identify specific residues of SLC51B essential for these processes. Among the diseases associated with SLC51B are
extrahepatic cholestasis, and biliary atresia.
Description
SLC51B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 95 amino acids (57-128 a.a) and having a molecular mass of 10.7kDa.
SLC51B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
SLC51B
protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol
and 0.1M NaCl.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSRSIQASR KEKMQPPEKE TPEVLHLDEA KDHNSLNNLR ETLLSEKPNL
AQVELELKER DVLSVFLPDV PETES
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
