Catalogue number
PRO-1763
Synonyms
Potassium Channel Tetramerization Domain Containing 4, Potassium
Channel Tetramerisation Domain Containing 4, bA321C24.3, BTB/POZ
Domain-Containing Protein KCTD4.
Introduction
KCTD4
also known as Potassium Channel Tetramerisation Domain Containing 4 has an N-terminal
homodimerization domain which contains multiple copies of kelch repeats and C2H2-type
zinc fingers. Proteins which include BTB domains are consider being involved in
transcriptional regulation through control of chromatin structure and function.
In addition, KCTD4 is a 259 amino acid protein which contains one BTB domain, a
possible role as a transcriptional regulator may be suggested.
Description
KCTD4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 282 amino acids (1-259 a.a) and having a molecular mass of 32.4kDa.
KCTD4 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
KCTD4 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 40%
glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles.
Purity
Greater
than 85% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMERKINR REKEKEYEGK HNSLEDTDQG KNCKSTLMTL NVGGYLYITQ
KQTLTKYPDT FLEGIVNGKI LCPFDADGHY FIDRDGLLFR HVLNFLRNGE LLLPEGFREN QLLAQEAEFF
QLKGLAEEVK SRWEKEQLTP RETTFLEITD NHDRSQGLRI FCNAPDFISK IKSRIVLVSK SRLDGFPEEF SISSNIIQFK YFIKSENGTR
LVLKEDNTFV CTLETLKFEA IMMALKCGFR LLTSLDCSKG SIVHSDALHF IK
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
