Catalogue number
PRO-1531
Synonyms
MSI2H, RNA-binding protein Musashi homolog 2, Musashi-2, MSI2.
Introduction
Musashi RNA-Binding Protein 2 (MSI2), is RNA binding protein which owns 2 conserved tandem RNA recognition motifs. MSI2 takes part in proliferation and maintenance of stem cells in the central nervous system. Comparable proteins in other species function as RNA-binding proteins and take part in posttranscriptional gene regulation.
Description
MSI2 Human Recombinant produced in E. coli is a single polypeptide chain containing 351 amino acids (1-328) and having a molecular mass of 37.6kDa. MSI2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
The MSI2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMEANGSQ GTSGSANDSQ HDPGKMFIGG LSWQTSPDSL RDYFSKFGEI RECMVMRDPT TKRSRGFGFV TFADPASVDK VLGQPHHELD SKTIDPKVAF PRRAQPKMVT RTKKIFVGGL SANTVVEDVK QYFEQFGKVE DAMLMFDKTT NRHRGFGFVT FENEDVVEKV CEIHFHEINN KMVECKKAQP KEVMFPPGTR GRARGLPYTM DAFMLGMGML GYPNFVATYG RGYPGFAPSY GYQFPGFPAA AYGPVAAAAV AAARGSGSNP ARPGGFPGAN SPGPVADLYG PASQDSGVGN YISAASPQPG SGFGHGIAGP LIATAFTNGY H.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
