Catalogue number
PRO-1207
Synonyms
FtsJ RNA methyltransferase homolog 2 (E. coli), putative ribosomal RNA methyltransferase 2, MRM2 RNA methyltransferase homolog, rRNA (uridine-2'-O-)-methyltransferase, cell division protein FtsJ, Protein ftsJ homolog 2, MRM2, FJH1, EC 2.1.1.-.
Introduction
FtsJ RNA Methyltransferase Homolog 2 (FTSJ2) belongs to the S-adenosylmethionine-binding protein family. FTSJ2 is a nucleolar protein and which is involved in cell cycle control and DNA repair and the processing and modification of rRNA. FTSJ2 is extensively expressed, with the highest expression in the muscle, placenta, and heart.
Description
FTSJ2 Human Recombinant produced in E. coli is a single polypeptide chain containing 219 amino acids (51-246) and having a molecular mass of 24.1 kDa.
FTSJ2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The FTSJ2 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 30% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSSYRCRSA FKLLEVNERH QILRPGLRVL DCGAAPGAWS QVAVQKVNAA GTDPSSPVGF VLGVDLLHIF PLEGATFLCP ADVTDPRTSQ RILEVLPGRR ADVILSDMAP NATGFRDLDH DRLISLCLTL LSVTPDILQP GGTFLCKTWA GSQSRRLQRR LTEEFQNVRI IKPEASRKES SEVYFLATQY HGRKGTVKQ
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
