Catalogue number
PRO-1941
Synonyms
CXADR-Like Membrane Protein, CLMP, Adipocyte Adhesion Molecule, Coxsackie- And Adenovirus Receptor-Like Membrane Protein, ACAM, ASAM, Adipocyte-Specific Adhesion Molecule, CAR-Like Membrane Protein, CSBS, CSBM.
Introduction
The CTX family of proteins (including ASAM) are type I transmembrane proteins within the Ig superfamily, which localize to junctional complexes between endothelial and epithelial cells and may play a role in cell-cell adhesion. CLMP has a role in adipocyte differentiation and development of obesity. CLMP is required for normal small intestine development.
Description
CLMP Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 233 amino acids (19-235) and having a molecular mass of 26.1 kDa.
CLMP is fused to a 16 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
The CLMP solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MASMTGGQQM GRGSHMTHTE IKRVAEEKVT LPCHHQLGLP EKDTLDIEWL LTDNEGNQKV VITYSSRHVY NNLTEEQKGR VAFASNFLAG DASLQIEPLK PSDEGRYTCK VKNSGRYVWS HVILKVLVRP SKPKCELEGE LTEGSDLTLQ CESSSGTEPI VYYWQRIREK EGEDERLPPK SRIDYNHPGR VLLQNLTMSY SGLYQCTAGN EAGKESCVVR VTVQYVQSIG MVA.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
