Catalogue number
PRO-1842
Synonyms
Guanine Nucleotide Binding Protein (G Protein) Gamma 4, Guanine Nucleotide-Binding Protein G(I)/G(S)/G(O) Subunit Gamma-4, GNGT4.
Introduction
GNG4 belongs to a multigene family and is involved in defining
the specificity of receptor-G protein interaction. In mammals, G protein alpha,
beta and gamma polypeptides are encoded by no less than 16, 4 and 7 genes,
respectively. It is a well-known fact that different G protein complexes
expressed in different tissues carry structurally distinct members of the alpha
beta and gamma subunits and that privileged connotation between members of
subunit families rise G protein functional diversity.
Description
GNG4 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 95 amino acids (1-72) and having a molecular mass of 10.4 kDa. GNG4 is fused to a 23 amino acid His-tag at N-terminus.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
The GNG4 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMKEGMSN NSTTSISQAR KAVEQLKMEA CMDRVKVSQA AADLLAYCEA HVREDPLIIP VPASENPFRE KKFFC
Safety Data Sheet
Usage
ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
