Catalogue number
PRO-2135
Synonyms
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3, Carcinoembryonic Antigen CGM1, CD66d Antigen , CD66D, CGM1, Carcinoembryonic Antigen Gene Family Member 1, Nonspecific Cross-Reacting Antigen, W264, W282, CEA, CEACAM3.
Introduction
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3, also known as
CEACAM3, is a member of the immunoglobulin super family. The genes in this
family encode cell adhesion proteins, which are expressed at higher levels in
tumorous tissues rather than in normal tissues. CEACAM3 plays a significant part
in the clearance of pathogens through the innate immune system. In addition,
CEACAM3 is accountable for RAC1 stimulation in the course of pathogen
phagocytosis.
Description
CEACAM3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 144 amino acids (35-155 a.a) and having a molecular mass of 15.5kDa.
CEACAM3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
CEACAM3 protein solution (0.25mg/ml) containing Phosphate buffered saline (pH7.4) and 20% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSKLTIESM PLSVAEGKEV LLLVHNLPQH LFGYSWYKGE RVDGNSLIVG YVIGTQQATP GAAYSGRETI YTNASLLIQN VTQNDIGFYT LQVIKSDLVN EEATGQFHVY QENAPGLPVG AVAG.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
