Catalogue number
ENZ-930
Synonyms
Phosphoglucomutase 2, Glucose Phosphomutase 2, Phosphodeoxyribomutase,
Phosphopentomutase, EC 5.4.2.2, PGM 2, Phosphoglucomutase-2, EC 5.4.2.7, EC
5.4.2, MSTP006.
Introduction
PGM2
or Phosphoglucomutase-2 is a protein of the alpha-d-phosphohexomutase family that
shares about 20% similarity with mammalian phosphoglucomutase 1. PGM2 Has low
glucose 1,6-bisphosphate synthase activity. Furthermore, PGM2 catalyzes the
conversion of the nucleoside breakdown products ribose-1-phosphate and
deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. In addition, PGM2 catalyzes the
interconversion of glucose-1-phosphate and glucose-6-phosphate.
Description
PGM2 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 635 amino acids (1-612 a.a) and
having a molecular mass of 70.7kDa. PGM2 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
PGM2 protein solution (1mg/ml) containing Phosphate
buffered saline (pH7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMAAPEGS GLGEDARLDQ ETAQWLRWDK NSLTLEAVKR LIAEGNKEEL
RKCFGARMEF GTAGLRAAMG PGISRMNDLT IIQTTQGFCR YLEKQFSDLK QKGIVISFDA RAHPSSGGSS
RRFARLAATT FISQGIPVYL FSDITPTPFV PFTVSHLKLC AGIMITASHN PKQDNGYKVY WDNGAQIISP HDKGISQAIE ENLEPWPQAW
DDSLIDSSPL LHNPSASINN DYFEDLKKYC FHRSVNRETK VKFVHTSVHG VGHSFVQSAF KAFDLVPPEA
VPEQKDPDPE FPTVKYPNPE EGKGVLTLSF ALADKTKARI VLANDPDADR LAVAEKQDSG EWRVFSGNEL GALLGWWLFT SWKEKNQDRS ALKDTYMLSS TVSSKILRAI
ALKEGFHFEE TLTGFKWMGN RAKQLIDQGK TVLFAFEEAI GYMCCPFVLD KDGVSAAVIS AELASFLATK
NLSLSQQLKA IYVEYGYHIT KASYFICHDQ ETIKKLFENL RNYDGKNNYP KACGKFEISA IRDLTTGYDD SQPDKKAVLP TSKSSQMITF TFANGGVATM RTSGTEPKIK
YYAELCAPPG NSDPEQLKKE LNELVSAIEE HFFQPQKYNL QPKAD.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
