Catalogue number
PRO-1055
Synonyms
Thioredoxin domain containing 17, Thioredoxin-like protein 5, Protein 42-9-9, thioredoxin (Trx)-related protein 14 kDa, TRP14, TXNL5, MGC14353.
Introduction
TXNDC17 is a disulfide reductase that takes part in several redox reactions using the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. TXNDC17 has peroxidase activity and assists to eliminate cellular hydrogen peroxide.
Description
TXNDC17 Human Recombinant produced in E. coli is a single polypeptide chain containing 147 amino acids (1-123) and having a molecular mass of 16.5kDa.
TXNDC17 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The TXNDC17 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 50mM Nacl and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSHMARYEE VSVSGFEEFH RAVEQHNGKT IFAYFTGSKD AGGKSWCPDC VQAEPVVREG LKHISEGCVF IYCQVGEKPY WKDPNNDFRK NLKVTAVPTL LKYGTPQKLV ESECLQANLV EMLFSED
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
