Catalogue number
PRO-1749
Synonyms
T-Cell Leukemia/Lymphoma 1B, Oncogene TCL-1B, Syncytiotrophoblast-Specific Protein, SYN-1, TML1, T-Cell Leukemia/Lymphoma Protein 1B, T-Cell Lymphoma/Leukemia 1B, TCL1/ MTCP1-Like 1, TCL1, Oncogene TCL1B, TCL1/MTCP1-Like Protein 1.
Introduction
T-cell
leukemia/lymphoma 1B, also known as TCL1B is a member of the TCL1 family. TCL1B
is expressed in a variety of tissues as well as the placenta and testis.
Moreover, TCL1B enhances the phosphorylation and activation of AKT1 and AKT2.
Description
TCL1B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 151 amino acids (1-128a.a) and having a molecular mass of 17.2kDa. TCL1B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
TCL1B protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 40% glycerol and 2mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles.
Purity
Greater than 95% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMASEASV RLGVPPGRLW IQRPGIYEDE EGRTWVTVVV RFNPSRREWA RASQGSRYEP SITVHLWQMA VHTRELLSSG QMPFSQLPAV WQLYPGRKYR AADSSFWEIA DHGQIDSMEQ LVLTYQPERK D
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
