Catalogue number
PRO-2153
Synonyms
CAMP
Responsive Element Binding Protein 3-Like 2, BBF2H7, CAMP-Responsive Element-Binding
Protein 3-Like Protein 2, BBF2 Human Homolog On Chromosome 7, Cyclic
AMP-Responsive Element-Binding Protein 3-Like Protein 2, Basic Transcription
Factor 2, B-ZIB Transcription Factor, FUS/BBF2H7 Protein, TCAG_1951439, Cyclic
AMP-responsive element-binding protein 3-like protein 2, cAMP-responsive
element-binding protein 3-like protein 2.
Introduction
CAMP Responsive Element Binding Protein 3-Like 2, also known as CREB3L2
belongs to the oasis bZIP transcription factor family. Members of this family
are able to dimerize however from homodimers only. CREB3L2 is a transcriptional
activator. Translocations between CREB3L2 on chromosome 7 and the gene fused in
sarcoma on chromosome 16 can be found in some tumors. One disease which is associated
with CREB3L2 is myxofibrosarcoma.
Description
CREB3L2 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 401 amino acids (1-378 a.a) and
having a molecular mass of 44kDa.
CREB3L2 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
CREB3L2 protein solution (0.25mg/ml) containing PBS (pH
7.4), 30% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMEVLESG EQGVLQWDRK LSELSEPGDG EALMYHTHFS ELLDEFSQNV
LGQLLNDPFL SEKSVSMEVE PSPTSPAPLI QAEHSYSLCE EPRAQSPFTH ITSDSFNDDE VESEKWYLST
DFPSTSIKTE PITDEPPPGL VPSVTLTITA ISTPLEKEEP
PLEMNTGVDS SCQTIIPKIK LEPHEVDQFL NFSPKEAPVD HLHLPPTPPS
SHGSDSEGSL SPNPRLHPFS LPQTHSPSRA APRAPSALSS SPLLTAPHKL QGSGPLVLTE EEKRTLIAEG
YPIPTKLPLS KSEEKALKKI RRKIKNKISA QESRRKKKEY MDSLEKKVES CSTENLELRK
KVEVLENTNR TLLQQLQKLQ TLVMGKVSRT CKLAGTQTGT C.
Safety Data Sheet
Usage
ProSpec's products are furnished for?LABORATORY RESEARCH?USE?ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
