Catalogue number
PRO-2084
Synonyms
Guanine
Nucleotide Binding Protein (G Protein), Gamma Transducing Activity Polypeptide
1, Transducin Gamma Chain, Guanine Nucleotide-Binding Protein G(T) Subunit
Gamma-T1, GNG1, Guanine nucleotide-binding protein G(T) subunit gamma-T1.
Introduction
Guanine Nucleotide Binding Protein Gamma Transducing 1, also known as
GNGT1 is amember of the G protein gamma family. GNGT1 is implicated in various
transmembrane signaling systems as a modulator or transducer.? In addition GNGT1 (beta & gamma chains)
is required for the GTPase activity, for replacement of GDP by GTP, and for G
protein- effector interaction.
Description
GNGT1 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 94 amino acids (1-71 a.a) and
having a molecular mass of 10.6kDa.
GNGT1 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
GNGT1 protein solution (1mg/ml) containing 20mM Tris-HCl
buffer (pH8.0), 10% glycerol, 0.1M NaCl and 1mM EDTA.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH
SSGLVPRGSH MGSMPVINIE
DLTEKDKLKM EVDQLKKEVT LERMLVSKCC EEVRDYVEER SGEDPLVKGI PEDKNPFKEL KGGC.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
