Catalogue number
PKA-314
Synonyms
DRAK1, Serine/threonine-protein kinase 17A, DAP
kinase-related apoptosis-inducing protein kinase 1, STK17A.
Introduction
STK17A belongs to the DAP
kinase-associated apoptosis-inducing protein kinase family and encodes an
autophosphorylated nuclear protein with a protein kinase domain. STK17A acts as
a positive regulator of apoptosis. STK17A is greatly expressed in the placenta
with lower levels in the heart, lung, skeletal muscle, kidney and pancreas.
Description
STK17A Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 281 amino acids (64-321 a.a) and
having a molecular mass of 31.9kDa.STK17A is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
STK17A protein solution (0.5mg/ml) contains 20mM Tris-HCl
buffer (pH 8.0), 10% glycerol and 0.4M Urea.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 80.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSGRELGRG KFAVVRKCIK KDSGKEFAAK FMRKRRKGQD CRMEIIHEIA
VLELAQDNPW VINLHEVYET ASEMILVLEY AAGGEIFDQC VADREEAFKE KDVQRLMRQI LEGVHFLHTR
DVVHLDLKPQ NILLTSESPL GDIKIVDFGL SRILKNSEEL REIMGTPEYV APEILSYDPI SMATDMWSIG
VLTYVMLTGI SPFLGNDKQE TFLNISQMNL SYSEEEFDVL SESAVDFIRT LLVKKPEDRA TAEECLKHPW L.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
