Catalogue number
ENZ-969
Synonyms
Aldolase, Fructose-Bisphosphate C, Aldolase C,
Fructose-Bisphosphate, Brain-Type Aldolase, EC 4.1.2.13, ALDC,
Fructose-1,6-Biphosphate Triosephosphate Lyase, Fructose-Bisphosphate Aldolase
C, Fructoaldolase C, Aldolase 3.
Introduction
Aldolase C Fructose-Bisphosphate (ALDOC) belongs to the class I fructose-bisphosphate aldolase family. ALDOC is a glycolytic enzyme which catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehydes respectively. ALDOC is expressed exclusively in the hippocampus and Purkinje cells of the brain.
Description
ALDOC Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 364 amino acids (1-364 a.a) and
having a molecular mass of 39.4kDa.
ALDOC is purified by proprietary chromatographic
techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
ALDOC protein solution (1mg/ml) containing 20mM Tris-Hcl
Buffer (pH 8.0), 20% glycerol, 2mM DTT and 0.1M NaCl.
Stability
Store at 4°C if entire vial will be used within 2-4
weeks.
Store, frozen at -20°C for longer periods of time.?
For long term storage it is recommended to add a carrier
protein (0.1% HSA or BSA).?
Avoid multiple freeze-thaw cycles.
Purity
Greater
than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MPHSYPALSA EQKKELSDIA LRIVAPGKGI LAADESVGSM AKRLSQIGVE
NTEENRRLYR QVLFSADDRV KKCIGGVIFF HETLYQKDDN GVPFVRTIQD KGIVVGIKVD KGVVPLAGTD
GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKISERTPS ALAILENANV LARYASICQQ NGIVPIVEPE
ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HVYLEGTLLK PNMVTPGHAC PIKYTPEEIA MATVTALRRT
VPPAVPGVTF LSGGQSEEEA SFNLNAINRC PLPRPWALTF SYGRALQASA LNAWRGQRDN AGAATEEFIK
RAEVNGLAAQ GKYEGSGEDG GAAAQSLYIA NHAY.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
