Catalogue number
PRO-1894
Synonyms
D3S3191, QCR1, UQCR1, Cytochrome b-c1 complex subunit 1, mitochondrial, Complex
III subunit 1, Core protein I, Ubiquinol-cytochrome-c reductase complex core
protein 1.
Introduction
Ubiquinol-Cytochrome C
Reductase Core Protein I (UQCRC1) is a member of the peptidase M16 family,UQCRC1/QCR1 subfamily. UQCRC1 is a part of the ubiquinol-cytochrome c
reductase complex (complex III or cytochrome b-c1 complex), which is component of
the mitochondrial respiratory chain. UQCRC1 can mediate formation of the
complex between cytochromes c and c1.
Description
UQCRC1 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 471 amino acids (35-480 a.a) and
having a molecular mass of 51.8kDa.UQCRC1 is fused to a 25 amino acid His-tag at N-terminus &
purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
UQCRC1 protein solution (1mg/ml) contains 20mM Tris-HCl buffer
(pH 8.0), 0.4M UREA and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSEFTATFA QALQFVPETQ VSLLDNGLRV ASEQSSQPTC TVGVWIDVGS RFETEKNNGA GYFLEHLAFK GTKNRPGSAL EKEVESMGAH LNAYSTREHT AYYIKALSKD LPKAVELLGD IVQNCSLEDS QIEKERDVIL REMQENDASM RDVVFNYLHA TAFQGTPLAQ AVEGPSENVR KLSRADLTEY LSTHYKAPRM VLAAAGGVEH QQLLDLAQKH LGGIPWTYAE DAVPTLTPCR FTGSEIRHRD DALPFAHVAI AVEGPGWASP DNVALQVANA IIGHYDCTYG GGVHLSSPLA SGAVANKLCQ SFQTFSICYA ETGLLGAHFV CDRMKIDDMM FVLQGQWMRL CTSATESEVA RGKNILRNAL VSHLDGTTPV CEDIGRSLLT YGRRIPLAEW ESRIAEVDAS VVREICSKYI YDQCPAVAGY GPIEQLPDYN RIRSGMFWLR F.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
