Catalogue number
ANT-492
Synonyms
Cytokine Receptor-Like Factor 2, Thymic Stromal Lymphopoietin Protein Receptor, Thymic Stromal-Derived Lymphopoietin Receptor, Cytokine Receptor CRL2 Precusor, P2RY8/CRLF2 Fusion, TSLP Receptor, TSLPR, IL-XR, CRL2, CRLF2Y, ILXR.
Type
Mouse Anti Human Monoclonal.
Introduction
Thymic Stromal Lymphopoietin Receptor (TSLPR) is a member of the type I cytokine receptor family. TSLPR alongside the interleukin 7 receptor (IL7R) activate STAT3, STAT5, and JAK2 pathways, which is regulated processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding dissimilar isoforms have been found for this gene. TSLPR is expressed in heart, skeletal muscle, kidney and ***** and fetal liver.
Clone
PAT4E7A.
Physical Appearance
Sterile filtered colorless solution.
Immunogen
Anti-human TSLPR mAb, clone PAT4E7A, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TSLPR protein 23-231 amino acids purified from E. coli.
Ig Subclass
Mouse IgG2a heavy chain and Kappa light chain.?
Purification Method
TSLPR antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Formulation
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Storage Procedures
For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C.?
Prevent freeze thaw cycles.
Stability / Shelf Life
12 months at -20°C. 1 month at 4°C.
Applications
TSLPR antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:5000. Recommended starting dilution is 1:1000.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
