Catalogue number
PRO-1772
Synonyms
Signal Sequence Receptor Alpha, Translocon-Associated
Protein Alpha, SSR Alpha Subunit, TRAP-alpha, TRAPA.
Introduction
SSR is a glycosylated endoplasmic reticulum (ER) membrane receptor involved in protein translocation across the ER membrane. SSR is formed of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. SSR gene creates a number of mRNA species due to complex alternative polyadenylation. SSR is unique since it exploits arrays of polyA signal sequences which are mostly non-canonical.
Description
SSR1 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain topological domain containing 209 amino
acids (22-207 a.a) and having a molecular mass of 23.1kDa. SSR1 is fused to a 23 amino
acid His-tag at N-terminus & purified by proprietary chromatographic
techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
SSR1 protein solution (0.25mg/ml) containing 20mM
Tris-HCl buffer (pH8.0), 0.1M NaCl, 1mM DTT and 20% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles.
Purity
Greater
than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSRGGPRGL LAVAQDLTED EETVEDSIIE DEDDEAEVEE DEPTDLVEDK
EEEDVSGEPE ASPSADTTIL FVKGEDFPAN NIVKFLVGFT NKGTEDFIVE SLDASFRYPQ DYQFYIQNFT
ALPLNTVVPP QRQATFEYSF IPAEPMGGRP FGLVINLNYK DLNGNVFQDA VFNQTVTVIE REDGLDGET
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
