Catalogue number
PRO-2196
Synonyms
Translationally-controlled tumor protein, TCTP, 21 kDa
polypeptide, p21, p23.
Introduction
TPT1 takes part in calcium binding and microtubule stabilization. TPT1 is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients. TPT1 protein is similar to p23, a protein of Ehrlich ascites tumor cells, synthesized in the exponentially growing tumor. TPT1 is similar with IgE-dependent histamine releasing factor. TPT1 has a cell housekeeping function. TPT1 is involved in spermatogenesis and acts as a calcium binding protein of the human placenta that regulates calcium handling in trophoblast cells.
Description
TPT1 Mouse Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 197 amino acids (1-172 a.a) and
having a molecular mass of 22.1kDa.
TPT1 is fused to a 25 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
TPT1 protein solution (1mg/ml) containing Phosphate
Buffered Saline, 10% glycerol
And 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4
weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier
protein (0.1% HSA or BSA).?
?Avoid multiple freeze-thaw cycles.
Purity
Greater
than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSHMMIIYR DLISHDELFS DIYKIREIAD GLCLEVEGKM VSRTEGAIDD
SLIGGNASAE GPEGEGTEST VVTGVDIVMN HHLQETSFTK EAYKKYIKDY MKSLKGKLEE QKPERVKPFM
TGAAEQIKHI LANFNNYQFF IGENMNPDGM VALLDYREDG VTPFMIFFKD GLEMEKC.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
