Catalogue number
PRO-2126
Synonyms
GP52-40, TSPAN26, Leukocyte antigen CD37, Tetraspanin-26,
Tspan-26.
Introduction
CD37 belongs to the transmembrane 4 superfamily, otherwise known as the tetraspanin family. Most of its members are cell-surface proteins which are distinguished by the presence of 4 hydrophobic domains. These proteins mediate signal transduction events which have a role in the regulation of cell development, activation, growth and motility. CD37 protein is a cell surface glycoprotein which is known to form complexes with integrins and other transmembrane 4 superfamily proteins. CD37 may also havea role in T-cell-B-cell interactions.
Description
CD37 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 154 amino acids (112-241 a.a) and having a molecular mass of 17.4kDa.
CD37 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
CD37 protein solution (1mg/ml) containing Phosphate
buffer saline, (pH 7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSQRAQLER SLRDVVEKTI QKYGTNPEET AAEESWDYVQ FQLRCCGWHY
PQDWFQVLIL RGNGSEAHRV PCSCYNLSAT NDSTILDKVI LPQLSRLGHL ARSRHSADIC AVPAESHIYR
EGCAQGLQKW LHNN.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
