Catalogue number
PRO-2184
Synonyms
Guanine Nucleotide Binding Protein (G Protein), Gamma 12,
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12.
Introduction
Guanine Nucleotide Binding Protein Gamma 12, also known as GNG12 belongs
to the Guanine nucleotide-binding proteins (G proteins) which are involved as a
modulator or transducer in a variety of transmembrane signaling systems. In
addition, the beta as well as gamma chains are essential for the GTPase
activity, for replacement of GDP by GTP, and also for G protein-effector interaction.
Description
GNG12 Human Recombinant produced in E.Coli is a single, non-glycosylated
polypeptide chain containing 92 amino acids (1-69 a.a) and having a molecular
mass of 10.1kDa.
GNG12 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
GNG12
protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10%
glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMSSKTAS TNNIAQARRT VQQLRLEASI ERIKVSKASA DLMSYCEEHA
RSDPLLIGIP TSENPFKDKK TC.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
