Catalogue number
PRO-2373
Synonyms
Oxidized
Low Density Lipoprotein Receptor 1, C-Type Lectin Domain Family 8 Member A, Lectin-Type
Oxidized LDL Receptor 1, CLEC8A, HLOX-1, LOX1, Oxidised Low Density Lipoprotein
(Lectin-Like) Receptor 1, Oxidized Low Density Lipoprotein (Lectin-Like)
Receptor 1, Oxidized Low-Density Lipoprotein Receptor 1, Soluble Form, Oxidized
Low-Density Lipoprotein Receptor 1, Scavenger Receptor Class E, Member 1, Lectin-Like
Oxidized LDL Receptor 1, Lectin-Like OxLDL Receptor 1, Ox LDL Receptor 1, Ox-LDL
Receptor 1, SCARE1, LOXIN, SLOX1, LOX-1, Oxidized low-density lipoprotein
receptor 1, Ox-LDL receptor 1, C-type lectin domain family 8 member A, LOX-1, Lectin-like
oxLDL receptor 1, hLOX-1, Lectin-type oxidized LDL receptor 1.
Introduction
| OLR1 is a type II membrane protein which belongs to the C-type lectin family and performs as a cell-surface receptor for Ox-LDL. Ox-LDL has a part in early ather-osclerosis, which includes the transformation of monocyte-derived macro-phages to foam cells in atherosclerotic lesions. In addition, OLR1 protein triggers the activation of the NF?B signal transduction pathway. |
Description
OLR1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 225 amino acids (58-273a.a) and having a molecular mass of 25.8kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).
OLR1 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Source
Sf9,
Baculovirus cells.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
OLR1
protein solution (1mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10%
glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95% as determined by SDS-PAGE.
Amino acid sequence
ADPMQLSQVS
DLLTQEQANL THQKKKLEGQ ISARQQAEEA SQESENELKE MIETLARKLN EKSKEQMELH HQNLNLQETL
KRVANCSAPC PQDWIWHGEN CYLFSSGSFN WEKSQEKCLS LDAKLLKINS TADLDFIQQA ISYSSFPFWM
GLSRRNPSYP WLWEDGSPLM PHLFRVRGAV
SQTYPSGTCA YIQRGAVYAE NCILAAFSIC QKKANLRAQH HHHHH.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
