Catalogue number
PRO-1863
Synonyms
WW and C2 domain containing 1, HBEBP3, HBEBP36, KIBRA, Protein KIBRA, HBeAg-binding protein 3, Kidney and brain protein, WW domain-containing protein 1, WWC1, KIAA0869.
Introduction
WW and C2 Domain Containing 1 (WWC1) is a cytoplasmic phosphoprotein which interacts with PRKC-zeta and dynein light chain-1. WWC1 takes part in cognition and memory performance. In some individuals, alleles of WWC1 have enhanced memory.
Description
WWC1 Human Recombinant produced in E. coli is. a single polypeptide chain containing 152 amino acids (655-783) and having a molecular mass of 17kDa. WWC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
The WWC1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSEAVGATR IQIALKYDEK NKQFAILIIQ LSNLSALLQQ QDQKVNIRVA VLPCSESTTC LFRTRPLDAS DTLVFNEVFW VSMSYPALHQ KTLRVDVCTT DRSHLEECLG GAQISLAEVC RSGERSTRWY NL.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
