Catalogue number
PRO-1229
Synonyms
CD84 Molecule, CD84 Antigen (Leukocyte Antigen), Cell Surface Antigen MAX.3, Leukocyte Differentiation Antigen CD84, Signaling Lymphocytic Activation Molecule 5, Leukocyte Antigen CD84, SLAM Family Member 5, SLAMF5, Hly9-Beta, LY9B, HCD84, MCD84.
Introduction
CD84 belongs to the signaling lymphocyte activation molecule (SLAM) family which forms a subset of the greater CD2 cell-surface receptor Ig superfamily. CD84, a membrane glycoprotein, is a homophilic adhesion molecule found in various immune cells types and takes part in regulating receptor-mediated signaling in those cells.
Description
CD84 Human Recombinant produced in E. coli is a single polypeptide chain containing 229 amino acids (22-225) and having a molecular mass of 25.4 kDa.
CD84 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The CD84 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 80% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSHMKDSEI FTVNGILGES VTFPVNIQEP RQVKIIAWTS KTSVAYVTPG DSETAPVVTV THRNYYERIH ALGPNYNLVI SDLRMEDAGD YKADINTQAD PYTTTKRYNL QIYRRLGKPK ITQSLMASVN STCNVTLTCS VEKEEKNVTY NWSPLGEEGN VLQIFQTPED QELTYTCTAQ NPVSNNSDSI SARQLCADIA MGFRTHHTG.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
