Catalogue number
CYT-713
Synonyms
Beta-Defensin 16, DEFB-16, Beta 16, defensin, Beta-Defensin
116, Defensin, Beta 16, DEFB16.
Introduction
Beta
Defensin 116, also known as DEFB116 is a member of the beta-defensin family.DEFB116
has antibacterial activity. The innate immune system includes antimicrobial peptides
that protect multicellular organisms from a diverse spectrum of microorganisms.
In addition, Beta-Defensins contain one important family of mammalian
antimicrobial peptides.
Description
DEFB116 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 102 amino acids (24-102 a.a) and having a molecular mass of 11.5kDa.
DEFB116 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
DEFB116 protein solution (0.5mg/ml) containing 20mM
Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 80.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSGLFRSHN GKSREPWNPC ELYQGMCRNA CREYEIQYLT CPNDQKCCLK LSVKITSSKN VKEDYDSNSN LSVTNSSSYS HI.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
