Catalogue number
PRO-2114
Synonyms
CD300e Molecule, CD300e Antigen, CD300LE, IREM2, CLM2, Immune Receptor Expressed On Myeloid Cells 2, Polymeric Immunoglobulin Receptor 2,CD300 Antigen Like Family Member E, CD300 Antigen-Like Family Member E,Poly-Ig Receptor 2, CMRF35-A5, PIgR2, CMRF35-Like Molecule 2, CMRF35A5, CD300E.
Introduction
CMRF35-like molecule 2 precursor (CD300E) is a member of the CD300 family. CD300E is a 205 amino acid single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. While interacting with DAP12, CD300E probably performs as an activating receptor. CD300E is present on the surface of mature hematopoietic cells of the monocyte & myeloid lineages.
Description
CD300E Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (18-173 a.a) and having a molecular mass of 19.9kDa.
CD300E is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
CD300E protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0).
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSLKGPGSV TGTAGDSLTV WCQYESMYKG YNKYWCRGQY DTSCESIVET KGEEKVERNG RVSIRDHPEA LAFTVTMQNL NEDDAGSYWC KIQTVWVLDS WSRDPSDLVR VYVSPAITTP RRTTHPATPP IFLVVNPGRN LSTGEVLTQN SGFRLSSPH.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
