T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, Erythrocyte receptor, Rosette receptor, CD2 antigen, CD2, T11, SRBC.
CD2 which is also known as E-rosette receptor, T11 and lymphocytefunction antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 plays a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.?
CD2 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 194 amino acids (25-209a.a.) and having a molecular mass of 22.3kDa (Molecular size on SDS-PAGE will appear at approximately 28-40 kDa).
CD2 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Sf9,
Baculovirus cells.
Sterile Filtered colorless solution.
CD2 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.?
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).?
Avoid multiple freeze-thaw cycles.
Greater than 95.0% as determined by SDS-PAGE.
ADPKEITNAL ETWGALGQDI NLDIPSFQMS DDIDDIKWEK TSDKKKIAQF RKEKETFKEK DTYKLFKNGT LKIKHLKTDD QDIYKVSIYD TKGKNVLEKI FDLKIQERVS KPKISWTCIN TTLTCEVMNG TDPELNLYQD GKHLKLSQRV ITHKWTTSLS AKFKCTAGNK VSKESSVEPV
SCPEKGLDHH HHHH.
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
