Catalogue number
PRO-2095
Synonyms
RALY Heterogeneous Nuclear Ribonucleoprotein, RNA-Binding
Protein (Autoantigenic, HnRNP-Associated With Lethal Yellow), HnRNP Associated
With Lethal Yellow Protein Homolog, Heterogeneous Nuclear Ribonucleoprotein
C-Like 2, HnRNP Core Protein C-Like 2, Autoantigen P542, HNRPCL2, P542, RNA
Binding Protein, Autoantigenic (HnRNP-Associated With Lethal Yellow Homolog
(Mouse)), RNA Binding Protein, Autoantigenic (HnRNP-Associated With Lethal
Yellow Homolog), RNA-Binding Protein (Autoantigenic), RNA-Binding Protein Raly,
RNA-binding protein Raly.
Introduction
RALY belongs to the heterogeneous nuclear ribonucleoprotein (hnRNP) gene
family. RALY takes part in pre-mRNA splicing and also in embryonic development.
Moreover, alternate splicing results in multiple transcript variants have been
found for RALY.
Description
RALY Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 329 amino acids (1-306 a.a) and
having a molecular mass of 34.9kDa.
RALY is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
RALY protein solution (0.5mg/ml) containing 20mM Tris-HCl
buffer (pH 8.0) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMSLKLQA SNVTNKNDPK SINSRVFIGN LNTALVKKSD VETIFSKYGR
VAGCSVHKGY AFVQYSNERH ARAAVLGENG RVLAGQTLDI NMAGEPKPDR PKGLKRAASA IYSGYIFDYD
YYRDDFYDRL FDYRGRLSPV PVPRAVPVKR PRVTVPLVRR
VKTNVPVKLF ARSTAVTTSS AKIKLKSSEL QAIKTELTQI KSNIDALLSR
LEQIAAEQKA NPDGKKKGDG GGAGGGGGGG GSGGGGSGGG GGGGSSRPPA PQENTTSEAG LPQGEARTRD
DGDEEGLLTH SEEELEHSQD TDADDGALQ.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
