Catalogue number
PRO-1399
Synonyms
Bos1, EPM6, GS27, Membrin, Golgi SNAP receptor complex member 2, 27 kDa Golgi SNARE protein, GOSR2.
Introduction
Golgi SNAP receptor complex member 2 isoform A (GOSR2) is a part of the SNARE Protein family which consists of important trafficking proteins between the endoplasmic reticulum and the Golgi and between Golgi subcompartments. GOSR2 is located near a locus implicated in familial essential hypertension, indicating that it is a potential candidate gene for this disease. GOSR2 exists as cytoplasmically oriented integral membrane proteins.
Description
GOSR2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 213 amino acids (1-190a.a) and having a molecular mass of 24.6kDa. GOSR2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
GOSR2 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1M Urea and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMDPLFQQ THKQVHEIQS CMGRLETADK QSVHIVENEI QASIDQIFSR LERLEILSSK EPPNKRQNAR LRVDQLKYDV QHLQTALRNF QHRRHAREQQ ERQREELLSR TFTTNDSDTT IPMDESLQFN SSLQKVHNGM DDLILDGHNI LDGLRTQRLT LKGTQKKILD IANMLGLSNT VMRLIEKRAF QDK.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
