Catalogue number
PRO-1210
Synonyms
Microfibrillar-Associated Protein 4, Microfibril-Associated Glycoprotein 4.
Introduction
Microfibrillar-associated protein 4 (MFAP4) is a member of Fibrinogen protein family and contains 1 fibrinogen C-terminal domain. The MFAP4 protein has similarity to a bovine microfibril-associated protein. MFAP4 has binding specificities for both collagen and carbohydrate. MFAP4 is believed to be an extracellular matrix protein that is involved in cell adhesion or intercellular interactions. MFAP4 deletion was found in 30 of 31 Smith-Magenis syndrome (SMS) patients.
Description
MFAP4 Human Recombinant produced in E. coli is a single polypeptide chain containing 259 amino acids (22-255) and having a molecular mass of 29.2 kDa.
MFAP4 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The MFAP4 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSHMVSGIR GDALERFCLQ QPLDCDDIYA QGYQSDGVYL IYPSGPSVPV PVFCDMTTEG GKWTVFQKRF NGSVSFFRGW NDYKLGFGRA DGEYWLGLQN MHLLTLKQKY ELRVDLEDFE NNTAYAKYAD FSISPNAVSA EEDGYTLFVA GFEDGGAGDS LSYHSGQKFS TFDRDQDLFV QNCAALSSGA FWFRSCHFAN LNGFYLGGSH LSYANGINWA QWKGFYYSLK RTEMKIRRA
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
