Catalogue number
PRO-1912
Synonyms
Glypican 4, Glypican Proteoglycan 4, K-glypican, DJ900E8.1
(Glypican 4), glypican-4.
Introduction
Glypican 4, also known as GPC4, is part of a family of
glycosylphosphatidylinositol (GPI)-anchored heparan sulphate proteoglycans
(HSPGs) which take part in the control of cell division and growth regulation.
GPC4 is broadly expressed in human tissues, including lung, kidney, heart,
placenta, skeletal muscle, and pancreas. In addition, GPC4 has been shown to be
present in astrocytes, haematopoietic-progenitor and bone-marrow-stromal cells.
Description
GPC4 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 165 amino acids (401-529a.a) and
having a molecular mass of 18kDa.
GPC4 is fused to a 36 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
GPC4 protein solution (0.25 mg/ml) containing 20mM
Tris-HCl buffer (pH 8.0), 0.1M NaCl and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles.
Purity
Greater
than 85% as determined by SDS-PAGE.
Amino acid sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSSSLP SNVCNDERMA AGNGNEDDCW NGKGKSRYLF AVTGNGLANQ
GNNPEVQVDT SKPDILILRQ IMALRVMTSK MKNAYNGNDV DFFDISDESS GEGSGSGCEY QQCPSEFDYN
ATDHAGKSAN EKADS
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
