Catalogue number
PRO-2189
Synonyms
C-Type
Lectin Domain Family 4, Member E, MINCLE, C-Type (Calcium Dependent,
Carbohydrate-Recognition Domain) Lectin, Superfamily Member 9, Macrophage-Inducible
C-Type Lectin, C-Type Lectin Superfamily Member 9, CLECSF9, C-Type Lectin
Domain Family 4 Member E, C-type lectin domain family 4 member E.
Introduction
C-type lectin domain family 4, member E, also known as CLEC4E is a C-type lectin receptor expressed through a wide range of antigens which presents cells including macrophages, neutrophils, dendritic cells as well as B cells; Furthermore, a variety of stimuli including stress are acknowledged to induce the expression of CLEC4E.
Description
CLEC4E Human Recombinant produced in E.Coli is a single, non-glycosylated
polypeptide chain containing 200 amino acids (41-219 a.a) and having a
molecular mass of 22.9kDa.
CLEC4E is fused to a 21 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
CLEC4E
protein solution (0.25mg/ml) containing 20mM Tris 8.0 and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH
SSGLVPRGSH MRCVVTFRIF
QTCDEKKFQL PENFTELSCY NYGSGSVKNC CPLNWEYFQS SCYFFSTDTI SWALSLKNCS AMGAHLVVIN
SQEEQEFLSY KKPKMREFFI GLSDQVVEGQ WQWVDGTPLT KSLSFWDVGE PNNIATLEDC ATMRDSSNPR
QNWNDVTCFL NYFRICEMVG INPLNKGKSL.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
