Catalogue number
PRO-1762
Synonyms
Jumonji Domain Containing 7, Jumonji Domain-Containing
Protein 7, JmjC Domain-Containing Protein 7.
Introduction
JmjC domain-containing protein 7 (JMJD7) is a member of the
JMJD family. JMJD7 encodes highly conserved proteins with a JmjC domain, which
are part of the cupin metalloenzyme superfamily. JMJD7 was first thought to be
an alternatively spliced isoform of PLA2G4B. It is derived from JMJD7 which is
located upstream of PLA2G4B. Most tissues also express read-through transcripts
from JMJD7 into the downstream PLA2G4B gene, some of which may encode fusion
proteins combining the N-terminus of JMJD7 with PLA2G4B protein.
Description
JMJD7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 339 amino acids (1-316 a.a) and having a molecular mass of 38.3kDa.
JMJD7 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
JMJD7 protein solution (1mg/ml) containing 20mM Tris-HCl
buffer (pH8.0), 10% glycerol and 0.1M NaCl.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles.
Purity
Greater
than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMAEAALE AVRSELREFP AAARELCVPL AVPYLDKPPT PLHFYRDWVC
PNRPCIIRNA LQHWPALQKW SLPYFRATVG STEVSVAVTP DGYADAVRGD RFMMPAERRL PLSFVLDVLE
GRAQHPGVLY VQKQCSNLPS ELPQLLPDLE SHVPWASEAL GKMPDAVNFW LGEAAAVTSL HKDHYENLYC VVSGEKHFLF HPPSDRPFIP
YELYTPATYQ LTEEGTFKVV DEEAMEKVPW IPLDPLAPDL ARYPSYSQAQ ALRCTVRAGE MLYLPALWFH
HVQQSQGCIA VNFWYDMEYD LKYSYFQLLD SLTKASGLD
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
