Catalogue number
PRO-2064
Synonyms
NudE Neurodevelopment Protein 1-Like 1, NUDEL, Mitosin-Associated
Protein 1, Protein Nudel, EOPA, MITAP1, NudE Nuclear Distribution E Homolog (A.
Nidulans)- Like 1, NudE Nuclear
Distribution Gene E Homolog (A. Nidulans)-Like 1, NDE1L1, NDE2, Endooligopeptidase
A, Mitosin-Associated Protein MITAP1, Nuclear Distribution Protein NudE-Like 1,
NudE Nuclear Distribution E Homolog-Like 1, NudE Nuclear Distribution Gene E
Homolog-Like 1, NDEL1.
Introduction
NudE Neurodevelopment Protein 1-Like 1 also known as NDEL1 is a
coiled-coil protein which participates in multiple processes as well as
cytoskeletal organization,
cell signaling and neuron migration,
outgrowth and maintenance. Alternatively
spliced transcript variants
encoding multiple isoforms have been observed for NDEL1, and a pseudogene of
this gene is placed on the
long arm of chromosome X. One of the diseases
associated with NDEL1 is iridocyclitis.
Description
NDEL1 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 351 amino acids (1-328 a.a) and
having a molecular mass of 39.4kDa.
NDEL1 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
NDEL1 protein solution (0.5mg/ml) containing 20mM
Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 80.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMDGEDIP DFSSLKEETA YWKELSLKYK QSFQEARDEL VEFQEGSREL
EAELEAQLVQ AEQRNRDLQA DNQRLKYEVE ALKEKLEHQY AQSYKQVSVL EDDLSQTRAI KEQLHKYVRE
LEQANDDLER AKRATIVSLE DFEQRLNQAI ERNAFLESEL
DEKESLLVSV QRLKDEARDL
RQELAVRERQ QEVTRKSAPS SPTLDCEKMD SAVQASLSLP ATPVGKGTEN TFPSPKAIPN GFGTSPLTPS ARISALNIVG
DLLRKVGALE SKLAACRNFA KDQASRKSYI SGNVNCGVLN GNGTKFSRSG HTSFFDKGQE KVIFPTLFMG Q.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
