Catalogue number
PRO-1669
Synonyms
Isochorismatase domain-containing protein 2, mitochondrial, ISOC2, Isochorismatase Domain Containing 2.
Introduction
Isochorismatase Domain Containing 2, also known as ISOC2, is a part of the isochorismatase family. SOC2 is localized in mitochondrion, cytoplasm, and nucleus. ISOC2 which interacts with CDKN2A is localizes to the nucleus in the attendance of CDKN2A.
Description
ISOC2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 170 amino acids (59-205) and having a molecular mass of 18kDa.
ISOC2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The ISOC2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSEQYPQGL GPTVPELGTE GLRPLAKTCF SMVPALQQEL DSRPQLRSVL LCGIEAQACI LNTTLDLLDR GLQVHVVVDA CSSRSQVDRL VALARMRQSG AFLSTSEGLI LQLVGDAVHP QFKEIQKLIK EPAPDSGLLG LFQGQNSLLH.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
