Catalogue number
PRO-1391
Synonyms
CHARC1, CHARC15, CHRAC-1, CHRAC-15, CHRAC15, YCL1, Chromatin accessibility complex protein 1, Chromatin accessibility complex 15 kDa protein, DNA polymerase epsilon subunit p15.
Introduction
Chromatin Accessibility Complex 1 (CHRAC1) is a histone-fold protein which interacts with further histone-fold proteins to bind DNA in a sequence-independent mode. These histone-fold protein dimers combine within larger enzymatic complexes for DNA replication, transcription, and packaging.
Description
CHRAC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 154 amino acids (1-131 a.a.) and having a molecular mass of 17.1kDa. CHRAC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
CHRAC1 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMADVVVG KDKGGEQRLI SLPLSRIRVI MKSSPEVSSI NQEALVLTAK ATELFVQCLA TYSYRHGSGK EKKVLTYSDL ANTAQQSETF QFLADILPKK ILASKYLKML KEEKREEDEE NDNDNESDHD EADS.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
