Catalogue number
PRO-2260
Synonyms
LDLR
chaperone MESD, Mesoderm development candidate 2, Mesoderm development protein,
Mesdc2, Mesd.
Introduction
Mesoderm development candidate 2 (MESDC2) is required for formation of the primitive streak and mesoderm during embryogenesis. MESDC2 binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression.
Description
MESDC2 Mouse Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 218 amino acids (30-224 a.a) and
having a molecular mass of 24.4kDa.?
MESDC2 is fused to a 23 amino acid His-tag
at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
MESDC2
protein solution (1mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10%
glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater
than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSADTPGEA TPPPRKKKDI RDYNDADMAR LLEQWEKDDD IEEGDLPEHK
RPSAPIDFSK LDPGKPESIL KMTKKGKTLM MFVTVSGNPT EKETEEITSL WQGSLFNANY DVQRFIVGSD
RAIFMLRDGS YAWEIKDFLV SQDRCAEVTL EGQMYPGKGG GSKEKNKTKP EKAKKKEGDP
KPRASKEDNR AGSRREDL.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
