Catalogue number
PRO-2210
Synonyms
Fibrinogen beta chain, Fibrinopeptide B, Fibrinogen, B
Beta Polypeptide,
Epididymis Secretory Sperm Binding Protein Li 78p, HEL-S-78p.
Introduction
Fibrinogen
Beta Chain 9 (FGB) is the beta component of fibrinogen, a blood-borne
glycoprotein composed of 3 pairs of nonidentical polypeptide chains. When vascular
injury accrues, fibrinogen is cleaved by thrombin to form fibrin which is found
in abundance in blood clots.
Description
FGB Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 351 amino acids (164-491a.a) and
having a molecular mass of 40kDa.?
FGB is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
FGB protein solution (1mg/ml) containing 20mM Tris-HCl buffer
(pH8.0) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.?
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).?
Avoid multiple freeze-thaw cycles.
Purity
Greater
than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSDNENVVN EYSSELEKHQ LYIDETVNSN IPTNLRVLRS ILENLRSKIQ
KLESDVSAQM EYCRTPCTVS CNIPVVSGKE CEEIIRKGGE TSEMYLIQPD SSVKPYRVYC DMNTENGGWT
VIQNRQDGSV DFGRKWDPYK QGFGNVATNT DGKNYCGLPG EYWLGNDKIS QLTRMGPTEL LIEMEDWKGD
KVKAHYGGFT VQNEANKYQI SVNKYRGTAG NALMDGASQL MGENRTMTIH NGMFFSTYDR DNDGWLTSDP
RKQCSKEDGG GWWYNRCHAA NPNGRYYWGG QYTWDMAKHG TDDGVVWMNW KGSWYSMRKM SMKIRPFFPQ Q.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
